All mammals have around 25,000 genes, yet humans are by far the most sophisticated. Our similar number of genes can code advanced processes because humans utilize thousands of commensal gut bacteria species to produce the precursors and chemical intermediates of human protein. Some bacteria even work in concert to produce a useful molecule. Human genes appear to begin few processes from absolute scratch. However, there may also be a downside to these bacteria. In 1907, Metchnikoff theorized rouge bacterial colonization of the colon was the cause of aging.
A decline in physical protein structure and increasing loss of function define aging. Diseases of aging all have in common a lack of collagen, peptides or hormones. Each of these proteins is formed only by the complete supply of all twenty amino acids. Lack of a single amino acid is enough to prevent production of a specific protein. Indeed. the first seen diseases of aging, hypertension and diabetes, are shown to be caused by a lack of control peptides.
The new theory is that gut bacteria are consuming more than a normal share of protein resource. This would lead to internal shortages of amino acids. The borrowing of specific amino acids from structure becomes necessary to continue life. Collagen of the face is usually the first site targeted. The missing collagen, “wrinkles,” become the first visible sign of aging.
Madame Jeanne Calment lived almost 123 years. Her sole unusual habit was to consume a bottle of port wine each night within an extended suppertime. In 2012, a molecule was isolated that naturally forms from extended contact of alcohol with amino acids. The new molecule allows that the specific and known missing amino acids are quickly absorbed.
The Metchnikoff theory was abandoned because researchers of the day could not isolate the ”toxin” they believed responsible for aging. There is still unwavering faith in existing orthodoxy. Competition for resource with common “gut bacteria” as the trigger of aging is not yet well accepted. It will be soon …because the new products are shown to work.
This section began by naming the basis of human evolution. The “poster child” for evolution is a small livebearer family of fishes, the Goodeid’s of Mexico. Goodeids can evolve into an entirely new species in only one generation. New ooloring, changes in behaviors, and diet change from full herbivore to full carnivore and everything in between are all possible in one generation. A pregnant female need only to drop her fry in a different body of water. The fry incorporate local bacteria to form an entirely new microbiome. As they develop, these characteristics can be passed on to offspring.